Here is a lifeform which has “solved” nanopond, which evolved after running the simulation for 14 hours; I find it unlikely that any new lifeforms can beat this one:
Translated, that is:
1 READG SHARE WRITEB INC SHARE TURN READG SHARE DEC WRITEG TURN READG SHARE LOOP FWD SHARE KILL READG WRITEB REP XCHG 0 STOP
There are two things that make this species strong: one, it shares almost randomly with cells around it, so it basically can eat energy from 5 cells around it instead of just the one it’s on; two, it rewrites its first nybble with a random(ish) one (one of its neighbors’ first nybbles minus one), so that nothing can evolve to kill its kind. Recall that to kill a cell you have to have the first nybble of that cell’s genome in your register when you do. Constantly changing your first nybble prevents that.